Buy FAB-144 Online

Description

Buy FAB-144 Online
Is a synthetic cannabinoid belonging to the family of indazole-based synthetic cannabinoids, structurally related to AB-FUBINACA and other substances designed to interact with the endocannabinoid system. Initially synthesized for research purposes, FAB-144 was later identified in designer drug products, often marketed as “legal highs” or sold as herbal incense mixtures under names like “Spice” or “K2.” Buy FAB-144 Online

It is considered part of the wider class of novel psychoactive substances (NPS), which continue to pose significant challenges to forensic toxicologists and public health authorities due to their evolving chemistry and severe adverse effects.

Chemical Identity and Structure

IUPAC Name: N-[[1-[(4-fluorophenyl)methyl]indazole-3-carbonyl]amino]-3,3-dimethylbutanamide

Molecular Formula: C₂₀H₂₃FN₄O₂

Molecular Weight: 370.42 g/mol

Chemical Class: Synthetic cannabinoid, indazole-based

Physical Appearance: White or off-white crystalline powder

FAB-144 is structurally similar to AB-FUBINACA, with slight alterations in the amide group, contributing to changes in its receptor binding profile and potentially increasing potency at CB₁ receptors.

Pharmacology and Mechanism of Action

Like other synthetic cannabinoids, FAB-144 is a full agonist at CB₁ and CB₂ receptors, unlike Δ9-THC (a partial agonist). This means it activates cannabinoid receptors more strongly and completely, often resulting in more intense psychoactive and physiological effects.

Reported pharmacological effects include:

Rapid onset of euphoria

Altered sensory and temporal perception

Motor impairment

Sedation or dissociation

Anxiety or panic reactions at higher doses

Toxicity and Adverse Effects

Use of FAB-144, especially in uncontrolled or unregulated contexts, is associated with severe and potentially life-threatening outcomes. Documented or suspected toxic effects include:

Acute psychosis and agitation

Tachycardia, hypertension

Nausea, vomiting, abdominal cramps

Respiratory depression

Seizures

Kidney or liver dysfunction

Loss of consciousness or coma

The narrow margin between psychoactive and toxic doses makes synthetic cannabinoids like FAB-144 particularly dangerous, especially when sold in pre-mixed or unlabeled products.

Legal and Regulatory Status

FAB-144 has been regulated in many countries under synthetic cannabinoid laws or emergency scheduling frameworks:

Controlled in the United States (often via analogue provisions of Schedule I)

Listed as a controlled substance in the UK, EU, China, and Japan

Monitored by the UNODC Early Warning Advisory on NPS

Its distribution, possession, or sale is illegal in most jurisdictions without explicit research exemption.

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