Pentylone (often referred to as bk-MBDP or β-keto-Methylbenzodioxolylpentanamine)
Is a synthetic cathinone and emerging psychoactive substance (EPS) that belongs to the bath salt family of stimulants. Commonly found in crystalline form, it has gained attention in both recreational and forensic contexts for its stimulant and empathogenic properties, somewhat similar to MDMA and methylone.
Chemical Identity and Structure
IUPAC Name: 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-oneCommon Name: PentyloneSynonyms: βk-MBDP, β-keto-MBDP, bk-PentyloneMolecular Formula: C₁₄H₁₉NO₃Molecular Weight: 249.31 g/molPhysical Form: White to off-white crystalline solid or powder💡 Structural Note:
Pentylone is structurally related to methylone, differing by having a longer side chain (pentyl instead of ethyl), which may affect its potency, duration, and lipid solubility.
Pharmacology and Mechanism of ActionPentylone acts primarily as a monoamine transporter inhibitor and releaser, impacting:Dopamine Transporter (DAT): Increases dopamine → stimulation, euphoriaSerotonin Transporter (SERT): Increases serotonin → mood elevation, empathyNorepinephrine Transporter (NET): Increases norepinephrine → alertness, cardiovascular stimulationIts pharmacological profile resembles MDMA + amphetamine, although less entactogenic and more stimulating at high doses.
Toxicity and Adverse Effects
Although Pentylone is sold under the guise of a “research chemical,” its safety is poorly studied in humans. Based on similar compounds, reported risks include:Short-Term Effects:
Increased energy and sociabilityElevated moodMild euphoriaSuppressed appetiteAdverse Reactions:
Cardiovascular: Elevated heart rate, blood pressure, palpitationsNeurological: Headache, agitation, tremorsPsychiatric: Anxiety, paranoia, insomnia, panicPhysical: Jaw clenching, dehydration, muscle crampsHigh doses or prolonged use may lead to hyperthermia, serotonin syndrome, or cardiac complications.
Legal StatusDue to its similarity to other synthetic cathinones, Pentylone is increasingly regulated:Country Legal Status
United States Schedule I (via Federal Analogue Act)
United Kingdom Class B under the Misuse of Drugs Act
EU Nations Controlled under national psychoactive substance laws
Australia Banned under cathinone analog laws
Canada Schedule I substance if intended for human use
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