Heroin, also known chemically as diacetylmorphine,

Is a powerful semi-synthetic opioid derived from morphine, which is naturally found in the opium poppy (Papaver somniferum). Originally developed in the late 19th century as a supposed non-addictive alternative to morphine, heroin quickly gained notoriety for its extreme addictive potential and euphoric effects. Today, it is classified as an illicit drug in most countries, strongly associated with substance abuse, overdose, and social harm.

Chemical and Pharmacological Profile

Heroin is usually found as a white or brown powder, or as a sticky black substance known as "black tar heroin." When consumed — by injecting, snorting, or smoking — heroin rapidly crosses the blood-brain barrier and is converted back into morphine.
It binds to mu-opioid receptors in the brain and spinal cord, triggering: Pain relief (analgesia) Euphoria Reduced anxiety Sedation and slowed breathing These effects, particularly the intense euphoria, drive repeated use and eventual dependence.
Short-Term Effects

After administration, users typically experience:
A rush of euphoria ("the high") Warm flushing of the skin Dry mouth Heaviness in limbs Drowsiness and confusion Slowed breathing and heart rate The high can last for several hours, followed by a "crash" or intense low that may provoke repeated use.
Long-Term Effects and Health Risks
With chronic use, heroin leads to severe physical and psychological consequences: Physical dependence and addiction Collapsed veins (from injection) Liver and kidney disease Infectious diseases like HIV/AIDS or hepatitis (from needle sharing) Cognitive decline and depression Respiratory depression, which can be fatal Withdrawal symptoms are intense and begin within hours of the last dose. These include: Muscle and bone pain Diarrhea and vomiting Cold flashes Severe cravings Restlessness and insomnia Overdose is a leading cause of death among users, often due to respiratory failure. It may be reversed by the emergency use of naloxone (Narcan) if administered in time.
Legal Status

Heroin is classified as a highly illegal substance across nearly all jurisdictions:
United States: Schedule I controlled substance — illegal with no accepted medical use United Kingdom: Class A drug — possession and supply are criminal offenses European Union: Strictly banned, with criminal penalties Asia and Middle East: Harsh legal penalties, including imprisonment or capital punishment in some countries Medical Exception: In a few countries (e.g., the UK and Switzerland), pharmaceutical-grade diamorphine is legally prescribed for severe chronic pain or in controlled heroin-assisted treatment (HAT) programs.
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