5F-ADB (5-fluoro-ADB; also known as 5F-MDMB-PINACA)

Is an exceptionally potent synthetic cannabinoid initially developed for pharmacological research into cannabinoid receptor activation. It rapidly entered the illicit market as a component in “herbal incense” products, where its extreme potency has been linked to numerous hospitalizations and fatalities. As a full agonist at CB₁ receptors, 5F-ADB presents a significant challenge to forensic toxicologists and public health authorities.

Chemical Identity and Structure

IUPAC Name: methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate
Common Names: 5F-ADB, 5F-MDMB-PINACA Chemical Class: Indazole-based synthetic cannabinoid Molecular Formula: C₂₀H₂₆FN₃O₃ Molecular Weight: 375.43 g/mol Physical Form: Fine white to off-white crystalline powder CAS Number: 1791551-37-8 Structurally, 5F-ADB features a fluorinated pentyl chain on an indazole core, coupled to a dimethylbutanoate ester, conferring high lipophilicity and strong receptor affinity.
Pharmacology and Mechanism of Action

5F-ADB acts as a full agonist at CB₁ and CB₂ cannabinoid receptors, with sub-nanomolar binding affinity at CB₁, vastly exceeding that of Δ9-THC. Key characteristics include:
Rapid onset: Effects felt within minutes when inhaled or vaporized High potency: Effective doses in the microgram range Duration: 2–4 hours, with peak psychoactivity in the first hour Activation of CB₁ receptors by 5F-ADB produces profound psychoactive effects such as intense euphoria, altered perception, and sedation. Its full agonism leads to physiological responses that are both stronger and less predictable than those of natural cannabinoids.
Toxicity and Adverse Effects

Due to its high potency and full agonist profile, 5F-ADB is associated with severe adverse events, including:
Neurological: seizures, agitation, tremors, acute psychosis Cardiovascular: tachycardia, hypertension, chest pain Respiratory: depressed breathing, potential respiratory arrest Renal & Hepatic: acute kidney injury, liver enzyme elevation Fatalities: multiple overdose deaths reported worldwide Even minute dosing errors can precipitate life-threatening toxicity. Emergency treatment often requires repeated high-dose naloxone (for respiratory support) and intensive supportive care.
How to buy 5F-ADB on line?
purchase from medlinepharam is easy and safe. without a doubt follow those steps: purchase our internet site - discover the 5F-ADB and pick the desired amount. upload to Cart - click on "Order Now" and go to the checkout. comfy payment - pick out one among several reliable bills alternatives. fast transport - we immediately technique your order and discreetly send it to your privacy.
Seeking out wherein to shop for an 5F-ADB on-line?
medlinepharma is your sincere supplier of pure studies chemicals. We offer clean ordering procedure, fast delivery and outstanding customer service. Order now! Do wait- order 5F-ADB online these days in medlinepharma and experience a safe, safe and expert shopping enjoy.