A-PPP (α-pyrrolidinopropiophenone) Is a synthetic stimulant belonging to the pyrrolidinophenone class of cathinones. Structurally similar to α-PVP and MDPV, A-PPP has gained attention as a novel psychoactive substance (NPS) and is typically encountered as a white crystalline powder in the designer drug market.
Chemical Identity and Structure
IUPAC Name: 1-Phenyl-2-(pyrrolidin-1-yl)propan-1-oneCommon Name: A-PPPSynonyms: α-PPP, alpha-PPP, alpha-pyrrolidinopropiophenoneMolecular Formula: C₁₃H₁₇NOMolecular Weight: 203.28 g/molAppearance: White to off-white crystalline powderChemical Class: Synthetic cathinone, β-keto amphetamine derivativeStructural Notes:
A-PPP contains a pyrrolidine ring, which is known to enhance central nervous system stimulation and increase lipid solubility, aiding in blood–brain barrier penetration.
Pharmacology and Mechanism of Action
A-PPP is believed to function as a dopamine and norepinephrine reuptake inhibitor (DNRI), though precise pharmacological data is limited.Key Effects:Increased dopamine: Euphoria, energy, compulsive behaviorIncreased norepinephrine: Alertness, agitation, cardiovascular stimulationMild serotonergic activity: (likely weak compared to dopamine/norepinephrine)A-PPP’s stimulant effects are short-acting, with onset occurring within 15–30 minutes (especially if insufflated or smoked) and lasting a few hours.
Toxicity and Adverse Effects
Although specific human studies on A-PPP are limited, its structure suggests a risk profile similar to α-PVP and MDPV, both of which are known for high abuse potential and neurotoxicity.Potential Adverse Effects:Neurological: Insomnia, paranoia, tremors, seizuresCardiovascular: Elevated heart rate, hypertension, palpitationsPsychiatric: Hallucinations, aggression, compulsive redosingPhysical: Hyperthermia, dehydration, jaw clenchingHigh doses or frequent use may lead to psychosis, addiction, or fatal overdose, particularly when mixed with other substances.
Analytical Detection
Standard drug tests may not detect A-PPP. Specialized forensic methods include:GC-MS (Gas Chromatography–Mass Spectrometry)LC-MS/MS (Liquid Chromatography–Tandem MS)FTIR and NMR Spectroscopy for structural confirmationDue to constant emergence of cathinone analogues, toxicology labs must regularly update detection libraries.
Legal Status
A-PPP may not always be explicitly scheduled but is often controlled under analogue laws or blanket bans on cathinones.United States: Likely controlled as a cathinone analogue (under the Federal Analogue Act)EU & UK: Covered by psychoactive substance regulationsCanada & Australia: May be restricted under controlled drug analoguesAsia (e.g., China, Japan): Banned under generic stimulant lawsDespite regulations, it remains available online or in underground markets, often labeled as a “research chemical”.How to buy FAB-144 on line?purchase from medlinepharam is easy and safe. without a doubt follow those steps: purchase our internet site - discover the FAB-144 and pick the desired amount. upload to Cart - click on "Order Now" and go to the checkout. comfy payment - pick out one among several reliable bills alternatives. fast transport - we immediately technique your order and discreetly send it to your privacy.Seeking out wherein to shop for an FAB-144 on-line?medlinepharma is your sincere supplier of pure studies chemicals. We offer clean ordering procedure, fast delivery and outstanding customer service. Order now! Do wait- order FAB-144 online these days in medlinepharma and experience a safe, safe and expert shopping enjoy.
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