ADB-FUBINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide)

Is a highly potent synthetic cannabinoid developed by Pfizer in 2009 during analgesic research. Later diverted into the recreational drug market, it rapidly gained global attention due to severe toxic effects, overdoses, and fatalities. It is a full agonist at CB₁ and CB₂ receptors, with much greater potency than Δ⁹-THC, the psychoactive component of natural cannabis.

Chemical Identity and Structure

IUPAC Name: N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide
Common Name: ADB-FUBINACA Chemical Class: Indazole-based synthetic cannabinoid Molecular Formula: C₂₀H₂₈FN₃O₃ Molecular Weight: 383.46 g/mol Physical Appearance: White or off-white crystalline powder The molecule includes an indazole core, 4-fluorobenzyl group, and dimethylbutanamide side chain, contributing to strong lipophilicity and blood–brain barrier penetration.
Pharmacology and Mechanism of Action

ADB-FUBINACA acts as a full agonist at:
CB₁ Receptors (Central Nervous System): Induces extreme psychoactivity, sedation, and hallucinations CB₂ Receptors (Peripheral Immune System): May influence immune function, but effects are less studied Binding affinity: CB₁ Ki ≈ 0.9 nM (extremely high potency) CB₂ Ki ≈ 0.5 nM Even microgram doses (as low as 0.3–1 mg) can cause intense intoxication, seizures, or unconsciousness.
Toxicity and Adverse Effects

ADB-FUBINACA is associated with numerous adverse and life-threatening effects:
Neurological: Confusion, seizures, blackouts, coma Cardiovascular: Bradycardia, hypotension, arrhythmias Respiratory: Depressed breathing or arrest Psychiatric: Psychosis, severe agitation, hallucinations, paranoia Fatalities: Linked to mass overdoses in the US, Russia, and Europe In 2016, over 30 people in New York City collapsed simultaneously after using synthetic cannabis containing ADB-FUBINACA — leading media to dub it “Zombie Outbreak.”
Legal Status and Control

Due to its extreme risk, ADB-FUBINACA is now controlled globally:
United States: Schedule I controlled substance UNODC: Recommended for international control in 2017 European Union: Controlled under synthetic cannabinoid regulations Australia, Canada, UK: Explicitly banned or controlled as an analogue Sale or possession, even in small quantities, is illegal in most jurisdictions.
Analytical Detection and Forensic Relevance

Standard drug screens do not detect ADB-FUBINACA. Advanced forensic tools are required:
LC-MS/MS: Primary method for detecting both the parent compound and its metabolites in biological samples GC-MS: Less common due to thermal instability HRMS (High-Resolution Mass Spectrometry): Used in toxicology and postmortem analysis Metabolite Analysis: Since the parent compound is often quickly broken down, detection often depends on specific metabolites
How to buy ADB-FUBINACA on line?

purchase from medlinepharam is easy and safe. without a doubt follow those steps: purchase our internet site - discover the FAB-144 and pick the desired amount. upload to Cart - click on "Order Now" and go to the checkout. comfy payment - pick out one among several reliable bills alternatives. fast transport - we immediately technique your order and discreetly send it to your privacy.

Seeking out wherein to shop for an ADB-FUBINACA on-line?

medlinepharma is your sincere supplier of pure studies chemicals. We offer clean ordering procedure, fast delivery and outstanding customer service. Order now! Do wait- order FAB-144 online these days in medlinepharma and experience a safe, safe and expert shopping enjoy