Valerylfentanyl Powder

Is a synthetic opioid and structural analog of fentanyl, one of the most potent painkillers ever created. Originally developed for research purposes, valerylfentanyl has emerged on the illicit drug market as part of the "designer opioid" wave. These substances are chemically tweaked versions of fentanyl designed to evade legal restrictions, yet they often retain—if not increase—the toxicity and overdose potential of their parent compound.
Though not approved for medical use, valerylfentanyl has been detected in drug seizures and overdose cases, raising serious public health and safety concerns.
Chemical Background

Valerylfentanyl (also known as N-(1-phenethylpiperidin-4-yl)-N-phenylvaleramide) belongs to the fentanyl analog family, sharing core similarities with fentanyl, sufentanil, and carfentanil. Small changes in chemical structure—such as replacing the propionyl group in fentanyl with a valeryl (pentanoyl) group—can result in significant changes in potency, duration, and side effect profiles.
It typically appears as a fine white or off-white powder and can be pressed into tablets, mixed into heroin, or sold as fentanyl—a practice that increases overdose risk dramatically.
Health Risks and Toxicity

Valerylfentanyl, like other fentanyl analogs, is extremely potent. It may be 100 to 1,000 times more powerful than morphine, though precise data for valerylfentanyl is limited. Known and suspected health risks include:
Fatal respiratory depression – the most common cause of death in overdoses Rapid tolerance and dependence, even after short-term use Withdrawal symptoms – intense cravings, pain, insomnia, and anxiety High overdose risk, especially when mixed with benzodiazepines or alcohol Unpredictable potency – especially in street formulations Difficulty in reversal – multiple doses of naloxone may be required to counteract an overdose Use of valerylfentanyl is linked to the ongoing opioid overdose crisis, particularly in North America.
Legal Status

Valerylfentanyl is illegal or controlled in most regions due to its similarity to fentanyl and extreme danger:
United States: Listed as a Schedule I Controlled Substance under the Controlled Substances Act United Kingdom: Classified as a Class A drug Canada: Prohibited as part of the Schedule I opioid class Germany, Sweden, and others: Controlled under national narcotics laws China: Banned due to concerns over synthetic opioid export Despite these regulations, its illegal manufacture and trafficking continue, often via online markets or as contaminants in street drugs.
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